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Evidence-Based Protocols

Microbiome Health Protocols

Structured, citation-backed protocols translating microbiome research into specific strains, doses, and phased plans. Read online or download the full PDF for your practitioner.

Each protocol synthesizes systematic reviews, meta-analyses, and randomized controlled trials into an actionable plan — covering the specific organisms involved, evidence-based supplement strains with clinical dosing, dietary strategy, and a phased timeline. These are educational resources, not medical advice; review any protocol with a qualified healthcare provider.

ADHD Gut-Brain Axis Protocol: Probiotics and Nutrients

Evidence-based gut-brain protocol for ADHD: clinical probiotic strains, omega-3, vitamin D, magnesium, zinc and iron dosing, backed by 16 peer-reviewed studies.

16 pages 16 citations Read →

Allergies & Hay Fever Microbiome Protocol: Gut-Lung Axis

Evidence-based hay fever and allergic rhinitis protocol: probiotic strains, prebiotic dosing, quercetin, and a two-phase plan to restore immune tolerance.

14 pages 15 citations Read →

Anxiety & Depression Microbiome Protocol: Gut-Brain Plan

An evidence-based 12-week gut-brain protocol for anxiety and depression: psychobiotic strains, prebiotic dosing, Mediterranean diet, and a phased timeline.

11 pages 16 citations Read →

Autism Spectrum Disorder Protocol: Gut-Brain Support

Evidence-based probiotic, vitamin D, omega-3, and diet strategies to support gut-brain health, GI comfort, and behavioral outcomes in autism spectrum disorder.

15 pages 16 citations Read →

Autoimmune Microbiome Protocol: RA, Hashimoto's & MS

Evidence-based gut protocol for autoimmune disease: a daily prebiotic shake, RCT-backed probiotic strains, and a two-phase plan for RA, Hashimoto's, and MS.

15 pages 19 citations Read →

Candida & Fungal Overgrowth Protocol: Evidence-Based Plan

Rebuild the bacterial colonization resistance that keeps Candida in check. Phased prebiotic, probiotic, and diet plan with dosing, backed by 16 studies.

12 pages 16 citations Read →

Cholesterol & Cardiovascular Health Protocol: Gut-Heart Axis

Evidence-based protocol to lower LDL and protect your heart through the gut-heart axis: BSH-active probiotics, berberine, omega-3 EPA, and beta-glucan.

16 pages 16 citations Read →

Common Cold & URTI Protocol: Gut-Lung Axis Immune Support

Evidence-based gut-lung axis protocol for the common cold and URTIs: prebiotic, probiotic, and dietary strategies tied to 24% fewer respiratory infections.

16 pages 16 citations Read →

Crohn's Disease Microbiome Protocol: Diet & Supplements

Evidence-based Crohn's disease protocol: CDED dietary therapy, S. boulardii, vitamin D, and omega-3 dosing to help support remission and reduce recurrence.

16 pages 18 citations Read →

Eczema & Atopic Dermatitis Protocol: Gut-Skin Axis Guide

Evidence-based gut-skin axis protocol for eczema and atopic dermatitis: probiotic strains with RCT data, prebiotic dosing, and a two-phase 12-week plan.

13 pages 16 citations Read →

Gut Restoration Protocol: Microbiome Repair After Antibiotics

Evidence-based gut restoration protocol to rebuild your microbiome after antibiotics: 3 phases, probiotic strains, prebiotic dosing, and barrier repair.

14 pages 14 citations Read →

Gut-Brain Cognitive Health & Dementia Prevention Protocol

Evidence-based gut-brain protocol for cognitive health: probiotic strains, omega-3, B vitamins, and the MIND diet, drawn from 16 peer-reviewed studies.

18 pages 16 citations Read →

Healthy Aging & Longevity Protocol: Gut Microbiome Guide

Evidence-based healthy aging protocol: centenarian microbiome signatures, Mediterranean diet, Akkermansia, urolithin A, and spermidine to extend healthspan.

14 pages 16 citations Read →

Histamine Intolerance Protocol: Gut, DAO Enzyme & Diet

Evidence-based histamine intolerance protocol covering gut dysbiosis, DAO enzyme support, histamine-safe probiotic strains, and a phased low-histamine diet.

14 pages 16 citations Read →

IBS Microbiome Protocol: Evidence-Based Gut Restoration

A 2-phase IBS microbiome protocol with clinically studied probiotic strains, prebiotic dosing, diet strategy, and 8-week timeline for IBS-D, IBS-C, and IBS-M.

12 pages 22 citations Read →

Lactose Intolerance Microbiome Protocol: Rebuild Tolerance

Evidence-based 12-week lactose intolerance protocol using GOS prebiotics, clinically studied probiotic strains, and gradual dairy reintroduction to build colonic adaptation.

13 pages 16 citations Read →

Metabolic Health Microbiome Protocol: Blood Sugar Plan

An evidence-based 12-week metabolic protocol: Akkermansia and multi-strain probiotic dosing, resistant starch targets, berberine, and biomarker tracking.

15 pages 15 citations Read →

Oral Microbiome & Dental Health Protocol: Evidence Guide

Evidence-based oral microbiome protocol: L. reuteri and S. salivarius strains with RCT data, xylitol dosing, the nitric oxide pathway, and a 6-month plan.

14 pages 16 citations Read →

PCOS Gut Microbiome Protocol: Probiotics, Inositol & Diet

Evidence-based PCOS protocol targeting the gut-hormone-microbiome axis: probiotic strains, myo-inositol dosing, berberine, vitamin D, and a phased 6-month plan.

15 pages 16 citations Read →

Pregnancy & Infant Microbiome Protocol: Conception to Year One

Evidence-based pregnancy and infant microbiome protocol: birth mode, HMOs, B. infantis EVC001 and L. rhamnosus HN001 dosing from preconception to age 2.

15 pages 16 citations Read →

Psoriasis & Skin Health Protocol: Gut-Skin Axis Guide

Evidence-based psoriasis protocol using the gut-skin axis: multi-strain probiotics with RCT data, vitamin D, omega-3, curcumin, and a 24-week phased plan.

15 pages 16 citations Read →

Respiratory & Immune Support Protocol: Gut-Lung Axis

Evidence-based respiratory and immune support protocol: gut-lung axis probiotic strains, vitamin D, zinc, and NAC dosing backed by 16 peer-reviewed studies.

16 pages 16 citations Read →

SIBO and IMO Microbiome Protocol: Eradicate and Prevent

A two-phase SIBO and IMO protocol with breath-test subtypes, rifaximin and herbal antimicrobial dosing, prokinetic therapy, diet strategy, relapse prevention.

17 pages 16 citations Read →

Sleep & Circadian Health Microbiome Protocol: Gut-Sleep Plan

An evidence-based 12-week gut-sleep protocol: L. gasseri CP2305 plus supporting strains, GOS prebiotic dosing, magnesium, L-theanine, 5-HTP, and a phased plan.

13 pages 19 citations Read →

Ulcerative Colitis Microbiome Protocol: Evidence-Based Plan

A two-phase ulcerative colitis microbiome protocol: VSL#3 dosing, E. coli Nissle 1917, curcumin, prebiotic timing, flare diet, and calprotectin tracking.

11 pages 15 citations Read →

Weight Management Microbiome Protocol: Gut & Metabolism

Evidence-based weight management protocol targeting the gut-metabolism axis: Akkermansia, L. gasseri SBT2055, berberine, SCFAs, and a 30-plant fiber plan.

14 pages 16 citations Read →

Women's Vaginal & Urinary Health Protocol: BV & UTI Plan

Restore Lactobacillus dominance to prevent recurrent BV and UTIs. Phased probiotic, D-mannose, and cranberry plan with strain-level dosing, from 16 studies.

15 pages 16 citations Read →